HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-methoxy-N-methyl-4-nitro-2'-methoxymethoxy-6'-methoxy-biphenyl-2-carboxamide → n-Methoxy-n-methyl-4-amino-2'-methoxymethoxy-6'methoxy-biphenyl-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-methoxy-N-methyl-4-nitro-2'-methoxymethoxy-6'-methoxy-biphenyl-2-carboxamide | HCID 18189308 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | n-Methoxy-n-methyl-4-amino-2'-methoxymethoxy-6'methoxy-biphenyl-2-carboxamide | HCID 18189391 | 104.2% |
Reaction Steps
A solution of Example 5B (5.67 g.) was dissolved in methanol (120 mL) and hydrogenated at 4 atm with 10% Pd/C (0.60 g) for 1 hour. The catalyst was removed by filtration and the solution concentrated to give the titled compound (5.44 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06593480B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-7a807d22a9be40d1bc313867527b100d |
| Source note | uspto-grants-2003_07 |