Hydrochloric Acid → HCID 18189442, compound

Participants

Reaction Steps

A solution of Example 51 (0.34 g, 0.76 mmol) in THF (5 mL) and ethanol (5 mL) was treated with a solution of 10% LiOH (5 mL), stirred at room temperature for 20 hours, and poured into a mixture of ice, 1M HCl (50 mL) and ethyl acetate (50 mL). The layers were separated, and the aqueous layer was extracted with ethyl acetate. The extract was dried (Na2SO4), filtered, and concentrated to provide the desired product.(0.26 g, 80%) as a white solid MS (ESI(−)Q1MS) m/z 424 (M−H)−.

Provenance & Evidence