2-Fluoroaniline → HCID 6469697, compound

HRID 1358191Notes

Reaction equation

HRID 1358191 reaction equation
[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[N:9]([C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]([O:21]C)=[O:20])=[CH:14][CH:13]=1)=[C:10]=[O:11]>>[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:10](=[O:11])[NH:9][C:12]1[CH:13]=[CH:14][C:15]([CH2:18][C:19]([OH:21])=[O:20])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 95842-FluoroanilineHCID 11183116HCID 11183116, compound

Product 1

HCID 6469697HCID 6469697, compound

Procedure

4-(2-Fluorophenyl)ureidophenylacetic acid was prepared using procedure C with 2-fluoroaniline and KCl: 1H NMR (CD3SOCD3, 300 MHz, ppm) 9.00 (s, 1H), 8.51 (d, 2.4 Hz, 1H), 8.14 (dd, 8.3 Hz, 1.5 Hz, 1H), 7.37 (d, 8.5 Hz, 2H), 7.07-7.25 (m, 4H), 6.99 (m, 1H), 3.48 (s, 2H).

Sources & evidence

ORD record
ord-0f122e2582544749a7b583b52bb515a6
Source dataset
uspto-grants-2003_07
Patent number
US06596687B1

Reaction notes

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