Ethanolamine → HCID 18184180, 화합물

HRID 1358355노트

반응식

HRID 1358355 반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([NH:11][C:12]2[C:17]([O:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[O:25][CH3:26])=[C:16](Cl)[N:15]=[C:14]([CH3:28])[N:13]=2)(=[O:10])=[O:9])=[N:6][CH:7]=1.[NH2:29][CH2:30][CH2:31][OH:32]>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([NH:11][C:12]2[C:17]([O:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[O:25][CH3:26])=[C:16]([O:32][CH2:31][CH2:30][NH2:29])[N:15]=[C:14]([CH3:28])[N:13]=2)(=[O:10])=[O:9])=[N:6][CH:7]=1

참가 물질

3

반응물 2

HCID 700EthanolamineHCID 227293975-methyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-2-pyridine sulfonamide

생성물 1

HCID 18184180HCID 18184180, 화합물

실험 절차

According to the procedure described in Example 4b) 1.00 g 5-methyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-2-pyridine sulfonamide was reacted with 2-aminoethanol to give 1.05 g 5-methyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-2-pyridine sulfonamide. LC-MS: tR=2.93 min, [M+1]+=446.51, [M−1]−=444.53.

출처 및 근거

ORD 기록
ord-59467b590b2c42a5982042514a7c1c95
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06596719B1

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