Trifluoromethanesulfonyl chloride → HCID 18184198, compound

Participants

Reaction Steps

According to the procedure described in Example 4a) 100 mg 5-isopropyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide was reacted with trifluoromethanesulfonylchloride to give 83 mg 5-isopropyl-N-[6-(2-(trifluoromethanesulfonylamino)-ethoxy)-5-(o-methoxyphenoxy)-2-(2-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide. LC-MS: tR=5.02 min, [M+1]+=669.59, [M−1]−=667.68.

Provenance & Evidence