p-Fluoronitrobenzene → HCID 18184777, compound

Participants

Reaction Conditions

Reaction Steps

1.3 g of sodium hydride are added to a solution of 7.8 g of 3,3,5,5-tetramethylcyclohexanol in 50 ml of dimethylformamide, and the mixture is stirred at 40-50° C. for 30 min. A total of 7.0 g of 4-fluoronitrobenzene are then added a little at a time, and the mixture is subsequently heated at 100° C. for three hours and cooled to room temperature. 250 ml of ice-water are added, the mixture is stirred and the resulting solid is filtered off with suction and dried under reduced pressure.

Provenance & Evidence