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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1358441Generated: October 26, 2026

5-(Trifluoromethyl)-1,3,4-oxadiazol-2-amine → 9H-Xanthene-9carboxylic acid (5-trifluoromethyl-[1,3,4]oxadiazol-2-yl)-amide

https://huagongshe.com/reaction/1358441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Trifluoromethyl)-1,3,4-oxadiazol-2-amineHCID 522630—
Reactant(3,5-dimethylpyrazol-1-yl)-(9H-xanthen-9-yl)methanoneHCID 4521579—
Product9H-Xanthene-9carboxylic acid (5-trifluoromethyl-[1,3,4]oxadiazol-2-yl)-amideHCID 53955883—

Reaction Steps

The title compound, white solid, m.p. 220-223° C.(decomp.), and MS: m/e=362.2 (M+H+) was prepared in accordance with the general method of example 48a from (3,5-dimethylpyrazol-1-yl)-(9H-xanthen-9-yl)-methanone and 5-trifluoromethyl-[1,3,4]oxadiazol-2-ylamine [U.S. Pat. No. 2,883,391].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06596743B2
Source datasetuspto-grants-2003_07
ORD IDord-74be9b5933b64962bfb4aad2778fc0d8
Source noteuspto-grants-2003_07