Hydrochloric Acid → HCID 69871283, compound

Participants

Reaction Steps

A mixture of methyl 2-ethoxy-3-[4-(1-methyl-6-methoxy-1H-benzimidazol-2-ylmethoxy)phenyl]propionate (0.17 g), concentrated hydrochloric acid (2 ml) and dioxane (2 ml) was heated at reflux for 1.5 hours. The reaction mixture was concentrated and the water of the residue was removed by azeotropic distillation in dioxane and the crystals were isolated by filtration to afford the title compound (0.16 g, mp 143-146° C.).

Provenance & Evidence