N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamide → HCID 21893383, compound

HRID 1358648Notes

Reaction equation

HRID 1358648 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=1.[CH:18]1([Mg]Cl)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:2]2[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 9927066N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamideHCID 178478990HCID 178478990, compound

Product 1

HCID 21893383HCID 21893383, compound

Procedure

The title product was prepared from the product of Example 27 as described in Example 15, Condition 2, with the exception that cyclohexylmagnesium chloride was used instead of cyclopentylmagnesium bromide.

Sources & evidence

ORD record
ord-822802d49c55440893304014f4f367aa
Source dataset
uspto-grants-2003_07
Patent number
US06596716B2

Reaction notes

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