1-Butanesulfonyl chloride → HCID 21893446, compound

HRID 1358669Notes

Reaction equation

HRID 1358669 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[CH2:26]([S:30](Cl)(=[O:32])=[O:31])[CH2:27][CH2:28][CH3:29]>>[CH2:26]([S:30]([NH:1][CH2:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=2)=[CH:8][CH:9]=1)(=[O:32])=[O:31])[CH2:27][CH2:28][CH3:29]

Participants

3

Reactant 2

HCID 754301-Butanesulfonyl chlorideHCID 21893565HCID 21893565, compound

Product 1

HCID 21893446HCID 21893446, compound

Procedure

The title compound was prepared following the method of Example 147 and using 1 mL of a stock solution of 0.5 g (1.4 mmol) of material from Example 50 and 10.4 μL (0.11 mmol) 1-butanesulfonyl chloride. NMR was consistent with the proposed compound.

Sources & evidence

ORD record
ord-a79af703136247e19094570aceb11699
Source dataset
uspto-grants-2003_07
Patent number
US06596716B2

Reaction notes

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