p-Phenylenediacetic acid → N-(4-Trifluoromethanesulfonyl-phenyl)-2-{4-[(4-trifluoromethanesulfonyl-phenylcarbamoyl)-methyl]-phenyl}-acetamide

Participants

Reaction Steps

Same procedure as Example 20 except 4-aminophenyl trifluoromethyl sulfone and 1,4-phenylenediacetic acid were used. 1H NMR (300 MHz, DMSO-d6) δ 10.90 (s, 2H, 2×NH), 8.04 (d, J=8.9 Hz, 4H), 7.99 (d, J=8.9 Hz, 4H), 7.84 (d, J=8.9 Hz, 2H), 7.23 (d, J=8.9 Hz, 2H), 3.71 (s, 4H, 2×CH2). MS 609 [M++1].

Provenance & Evidence