HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-[4-(4-Dimethylaminosulfonylbenzyl)-phenyl]amino-imidazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloroimidazoline sulfate | HCID 12503398 | — |
| Reactant | 4-(4-Dimethylaminosulfonylbenzyl)-phenylamine | HCID 21877038 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-[4-(4-Dimethylaminosulfonylbenzyl)-phenyl]amino-imidazoline | HCID 12094387 | 164.4% |
Reaction Steps
A mixture of 4-(4-dimethylaminosulfonylbenzyl)-phenylamine (288 mg) and 2-chloro-imidazoline sulfate (110 mg) in 2-propanol was heated under reflux for 16 hours. A dilute solution of potassium carbonate was poured into the mixture and extracted with dichloromethane (4×15 mL). Solvents were evaported to give 2-[4-(4-dimethylaminosulfonylbenzyl)-phenyl]amino-imidazoline as a solid (320 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06596876B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-dead42ba181b413a97774bc122290e3a |
| Source note | uspto-grants-2003_07 |