HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,5,5,5-Pentafluoropent-2-en-l-ol → 4,4,5,5,5-Pentafluoropentan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,5,5,5-Pentafluoropent-2-en-l-ol | HCID 54452699 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4,4,5,5,5-Pentafluoropentan-1-ol | HCID 547967 | — |
Reaction Steps
10 g of 4,4,5,5,5-pentafluoro-2-penten-1-ol (obtained according to J. Am. Chem. Soc., 107, (1985), 5186-5191: T. Kitazume and N. Ishikawa) is dissolved in 100 cm3 of methanol, and hydrogenation is carried out in the presence of 0.5 g of Raney nickel. The catalyst is filtered, followed by washing with ethanol and after distillation at ordinary pressure, the expected alcohol is collected B.p.: 133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06596885B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-9942ef1831e346a284d25834828bc172 |
| Source note | uspto-grants-2003_07 |