Dimethylformamide diethylacetal → HCID 54313961, compound

HRID 1358992Notes

Reaction equation

HRID 1358992 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH2:9][C:10]2=[O:13])=[CH:5][CH:4]=1.C(O[CH:17](OCC)[N:18]([CH3:20])[CH3:19])C>>[CH3:17][N:18]([CH:20]=[C:9]1[CH2:8][CH2:7][C:6]2[C:11](=[CH:12][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[C:10]1=[O:13])[CH3:19]

Participants

3

Reactant 2

HCID 70913Dimethylformamide diethylacetalHCID 812767-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one

Product 1

HCID 54313961HCID 54313961, compound

Procedure

The 3,4-dihydro-2-(dimethylaminomethylene)-7-methoxy-1(2H)-naphthalenone starting material was prepared from 7-methoxy-1-tetralone (5.0 g, 28.4 mmol) and N,N-dimethylformamide diethyl acetal (10 ml, 58.3 mmol) ito give the desired product as a yellow solid (1.28 g). m.p. 95.1 °. MS (ES+) 232 (MH+, 100%).

Sources & evidence

ORD record
ord-1d21521622004846a75e6a6d60173b4e
Source dataset
uspto-grants-2003_07
Patent number
US06599908B1

Reaction notes

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