Thiochroman-4-one → HCID 54032814, compound

HRID 1358995Notes

Reaction equation

HRID 1358995 reaction equation
[S:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH2:3][CH2:2]1.C(O[CH:15](OCC)[N:16]([CH3:18])[CH3:17])C>>[CH3:15][N:16]([CH:18]=[C:3]1[CH2:2][S:1][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:11])[CH3:17]

Participants

3

Reactant 2

HCID 19048Thiochroman-4-oneHCID 70913Dimethylformamide diethylacetal

Product 1

HCID 54032814HCID 54032814, compound

Procedure

The 3,4-dihydro-2-(dimethylaminomethylene)-4-thia-1(2H)-naphthalenone starting material was prepared from thiochroman-4-one (4.93 g, 26.8 mmol) and N,N-dimethylformamide diethyl acetal (23 ml, 133.8 mmol) to give the desired product as golden yellow crystals (5.15 g) m.p. 96-97°. MS (ES+) 220 (MH+, 100%).

Sources & evidence

ORD record
ord-ebfc5e5147b04be7805bf352862e2721
Source dataset
uspto-grants-2003_07
Patent number
US06599908B1

Reaction notes

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