HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide diethylacetal → 6-chloro-2,3-dihydro-3-dimethylaminomethylene-4H-1-benzothiopyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide diethylacetal | HCID 70913 | — |
| Reactant | 6-Chlorothiochroman-4-one | HCID 248065 | — |
| Product | 6-chloro-2,3-dihydro-3-dimethylaminomethylene-4H-1-benzothiopyran-4-one | HCID 3813536 | — |
Reaction Steps
The 7-chloro-3,4-dihydro-2-(dimethylaminomethylene)-4-thia-1(2H)-naphthalenone starting material was prepared from 6-chloro-thiochroman-4-one (3.97 g, 20 mmol) and N,N-dimethylformamide diethyl acetal (20 ml, 80 mmol) to give the desired product as yellow crystals (4.38 g) m.p. 127-128°. MS (ES+) 256 (MH+, 37Cl, 33%), 254 (MH+, 35Cl, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06599908B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-97145b46c0a344e3a421736abcac3474 |
| Source note | uspto-grants-2003_07 |