HRID1359001

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID9864

Cyanamide

CH2N2

HCID6484655

4-[2-(dimethylamino)ethoxy]aniline

C10H16N2O

结构：COc1cc(NC(N)=[NH2+])cc(OC)c1OC.O=[N+]([O-])[O-]

HCID178419082

未命名化合物

PRODUCTS

生成物

结构：CN(C)CCOc1ccc(NC(N)=[NH2+])cc1.CN(C)CCOc1ccc(NC(N)=[NH2+])cc1.O=[N+]([O-])[O-].O=[N+]([O-])[O-]

HCID178483888

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID944

Nitric Acid

HNO3

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

4-(2-Dimethylaminoethoxy)phenylguanidinium dinitrate was prepared by the method described for 3,4,5-trimethoxyphenylguanidinium nitrate in Example 1 from 4-(2-dimethylaminoethoxy)aniline (5.0 g, 28 mmol), cyanamide (1.75 g, 41 mmol) in water (3.5 ml) and concentrated nitric acid (4 ml) to give the product as a light purple solid (6.8 g) m.p. 149-152°. MS (ES+) 223 (MH+, 100%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6991fd2398c44d58870e29931b7c17d3
来源数据集: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06599908B1
来源说明: uspto-grants-2003_07

反应 SMILES

[N+:1]([O-:4])([O-:3])=[O:2].CO[C:7]1[CH:8]=[C:9]([NH:17][C:18]([NH2:20])=[NH2+:19])[CH:10]=[C:11](OC)[C:12]=1[O:13][CH3:14].[CH3:21][N:22]([CH3:33])[CH2:23][CH2:24][O:25][C:26]1[CH:32]=[CH:31][C:29]([NH2:30])=[CH:28][CH:27]=1.[N:34]#[C:35][NH2:36]>O.[N+]([O-])(O)=O>[N+:1]([O-:4])([O-:3])=[O:2].[N+:1]([O-:4])([O-:3])=[O:2].[CH3:21][N:22]([CH3:33])[CH2:23][CH2:14][O:13][C:12]1[CH:11]=[CH:10][C:9]([NH:17][C:18]([NH2:20])=[NH2+:19])=[CH:8][CH:7]=1.[CH3:21][N:22]([CH2:23][CH2:24][O:25][C:26]1[CH:32]=[CH:31][C:29]([NH:30][C:35]([NH2:36])=[NH2+:34])=[CH:28][CH:27]=1)[CH3:33]