Dimethylformamide diethylacetal → HCID 54509978, compound

HRID 1359009Notes

Reaction equation

[CH3:1][C:2]1([CH3:13])[S:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:12])[CH2:3]1.C(O[CH:17](OCC)[N:18]([CH3:20])[CH3:19])C>>[CH3:17][N:18]([CH:20]=[C:3]1[C:2]([CH3:13])([CH3:1])[S:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:12])[CH3:19]

Participants

Reactant 2

HCID 70913Dimethylformamide diethylacetal

HCID 82487628035-02-1

Product 1

HCID 54509978HCID 54509978, compound

Procedure

3,4-dihydro-2-dimethylaminomethylene-3,3-dimethyl-4-thia-1(2H)-naphthalenone was prepared from 3,4-dihydro-3,3-dimethyl-4-thia-1(2H)naphthalenone (426 mg, 1.72 mmol) [Clayton, S E et al, Tetrahedron (1993), 49, 939], and N,N-dimethylformamide diethyl-acetal (1 ml) to give the compound as a yellow solid (113 mg). δH (CDCl3) 8.22 (1H, dd, J 1.6, 7.9 Hz), 7.32-7.14 (3H, m), 6.72 (1H, s), 2.89 (6H, s) and 1.63 (6H, s).

Sources & evidence

ORD record: ord-b744d432dd9e4ad095b84db56a049bb8
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06599908B1

Reaction notes

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