Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Flecainide → 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Flecainide | HCID 3356 | — |
| 반응물 | 2,5-Dihydroxybenzoic acid | HCID 3469 | — |
| 반응물 | 2,2,2-Trifluoroethyl perfluorobutylsulfonate | HCID 2777144 | — |
| 생성물 | 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate | HCID 11281014 | — |
반응 단계
Process for the synthesis of FLECAINIDE comprising the reaction between 2,5-dihydroxybenzoic acid with trifluoroethanol perfluorobutanesulphonate to give the intermediate trifluoroethanol 2,5-bis-trifluoroethoxybenzoate, the reaction of said intermediate with 2-aminomethylpiperidine to give FLECAINIDE.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06599922B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-362bf334465f4aea9bd4cda8d16c6c78 |
| 출처 메모 | uspto-grants-2003_07 |