Potassium Carbonate → (3R)-3-ethynyl-1-azabicyclo[2.2.2]octan-3-ol

Participants

Reaction Steps

15.6 g of (3R)-3-ethynyl-3-quinuclidinol +L-(+)-tartrate was dissolved in 150 ml of water and 20 g of anhydrous potassium carbonate was added little by little under stirring. The resulting crystal were collected by filtration, washed with water and then dried, to give 6.88 g of the title compound.

Provenance & Evidence