HCID 69758673, compound → HCID 18182433, compound

HRID 1359302Notes

Reaction equation

HRID 1359302 reaction equation
[CH2:1]([C:8]1[C:9]([O:21][CH3:22])=[N:10][CH:11]=[C:12]([CH:14]=[CH:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>[C].[Pd].C(O)C>[CH2:1]([C:8]1[C:9]([O:21][CH3:22])=[N:10][CH:11]=[C:12]([CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 69758673HCID 69758673, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18182433HCID 18182433, compoundYield 99.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

A mixture of 950 mg of 3-benzyl-5-(2-ethoxycarbonylethenyl)-2-methoxypyridine, 90 mg of 10% palladium carbon and 10 ml of ethanol was stirred at room temperature for one hour in a hydrogen atmosphere. After the atmosphere in the system was replaced by nitrogen, the mixture was filtered through Celite. The solvent was removed, to give 950 mg of the target compound.

Workup

  1. filtrationthe mixture was filtered through Celite
  2. customThe solvent was removed

Sources & evidence

ORD record
ord-e27b394337fc48d09b5aa0a308fecd0a
Source dataset
uspto-grants-2003_07
Patent number
US06599917B1

Reaction notes

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