HCID 69760052, compound → HCID 770061, compound

HRID 1359324Notes

Reaction equation

HRID 1359324 reaction equation
C([O:8][C:9]1[C:10]([CH:16]=[CH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:11][C:12]([CH3:15])=[CH:13][CH:14]=1)C1C=CC=CC=1>CO.[C].[Pd]>[OH:8][C:9]1[C:10]([CH2:16][CH2:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[N:11][C:12]([CH3:15])=[CH:13][CH:14]=1

Participants

4

Reactant 1

HCID 69760052HCID 69760052, compound

Product 1

HCID 770061HCID 770061, compoundYield 81.8%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

1.2 g of 3-benzyloxy-6-methyl-2-styrylpyridine was dissolved in 20 ml of methanol. 684 mg of 10% palladium carbon was added thereto, and the mixture was to hydrogenated. The atmosphere in the reaction system was replaced by nitrogen and the catalyst was filtered off. The filtrate was evaporated, to give 695 mg of the target compound.

Workup

  1. filtrationthe catalyst was filtered off
  2. customThe filtrate was evaporated

Sources & evidence

ORD record
ord-600b7235295348dd95575dbe9a3b390d
Source dataset
uspto-grants-2003_07
Patent number
US06599917B1

Reaction notes

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