HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethanol → HCID 305582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Captamine Hydrochloride | HCID 25798 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 305582 | HCID 305582 | — |
Reaction Steps
2-(Dimethylamino)ethanethiol hydrochloride (Aldrich) is treated with NaOH (0.2N) in ethanol (95%). To this slurry, 2-bromoethanol (1.2 eq.) is added and the mixture is refluxed for 2 hours. The reaction mixture is cooled, filtered and concentrated. The resultant residue is purified by silica gel flash column chromatography to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06600032B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-790b4123d55446d18abd68d8039ab116 |
| Source note | uspto-grants-2003_07 |