HuagongsheHuagongshe Chemistry Print Report · For research reference only
rel-(2R,6S)-2,6-dimethylpiperazine → 4-[(cis)-3,5-dimethyl-piperazine-1-carbonyl]-3-methyl-1H-pyrrole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | rel-(2R,6S)-2,6-dimethylpiperazine | HCID 6950261 | — |
| Reactant | 5-Formyl-4-methyl-1H-pyrrole-3-carboxylic acid | HCID 22135453 | — |
| Product | 4-[(cis)-3,5-dimethyl-piperazine-1-carbonyl]-3-methyl-1H-pyrrole-2-carbaldehyde | HCID 20761533 | 88% |
Reaction Steps
5-Formyl-4-methyl-1H-pyrrole-3-carboxylic acid (1.00 g, 6.54 mmol) reacted with cis-2,6-dimethylpiperazine (822 mg, 7.19 mmol) to give 1.43 g (88%) of 4-[(3R,5S)-3,5-dimethyl-piperazine-1-carbonyl]-3-methyl-1H-pyrrole-2-carbaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06599902B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-01fdc88499874374ac882d16104659dc |
| Source note | uspto-grants-2003_07 |