Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359700Generated: October 25, 2026

5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid → 5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

https://huagongshe.com/reaction/1359700

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic AcidHCID 11073792—
Reactant5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-oneHCID 18179768—
Product5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acidHCID 59077507—

Reaction Steps

5-(2,6-Dichlorophenylmethanesulfonyl)-1,3-dihydro-indol-2-one was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid using the general condensation method to give 5-[5-(2,6-dichlorophenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-65b28d72ef4c4b1ea65021b26fbff187
Source noteuspto-grants-2003_07