Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359708Generated: October 27, 2026

1-Pyrrolidinepropanamine → 5-[5-(2,6-Dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-Pyrrolidin-1-yl-propyl)-amide

https://huagongshe.com/reaction/1359708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PyrrolidinepropanamineHCID 31670—
Reactant5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acidHCID 59077507—
Product5-[5-(2,6-Dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-Pyrrolidin-1-yl-propyl)-amideHCID 59077697—

Reaction Steps

5-[5-(2,6-Dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid was coupled with 3-pyrrolidin-1-yl-propylamine to give the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-fbffc54450dc4abfbffcedddc6ef231b
Source noteuspto-grants-2003_07