1-Pyrrolidineethanamine → HCID 59077706, compound

HRID 1359710Notes

Reaction equation

HRID 1359710 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH2:9][S:10]([C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17](=[O:22])/[C:16]/2=[CH:23]\[C:24]1[NH:25][C:26]([CH3:32])=[CH:27][C:28]=1[C:29]([OH:31])=O)(=[O:12])=[O:11].[N:33]1([CH2:38][CH2:39][NH2:40])[CH2:37][CH2:36][CH2:35][CH2:34]1>>[N:33]1([CH2:38][CH2:39][NH:40][C:29]([C:28]2[CH:27]=[C:26]([CH3:32])[NH:25][C:24]=2/[CH:23]=[C:16]2\[C:17](=[O:22])[NH:18][C:19]3[C:15]\2=[CH:14][C:13]([S:10]([CH2:9][C:3]2[C:4]([Cl:8])=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])(=[O:12])=[O:11])=[CH:21][CH:20]=3)=[O:31])[CH2:37][CH2:36][CH2:35][CH2:34]1

Participants

3

Reactant 2

HCID 13441-PyrrolidineethanamineHCID 59077650HCID 59077650, compound

Product 1

HCID 59077706HCID 59077706, compound

Procedure

2-[5-(2,6-Dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-5-methyl-1H-pyrrole-3-carboxylic acid was coupled with 2-pyrrolidin-1-yl-ethylamine to give the titled compound.

Sources & evidence

ORD record
ord-a1f84b20bf76481a90ba4aad0037e868
Source dataset
uspto-grants-2003_07
Patent number
US06599902B2

Reaction notes

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