5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid → HCID 59077738, compound

HRID 1359770Notes

Reaction equation

HRID 1359770 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:3]=1[CH2:4][S:5]([C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11]2)(=[O:7])=[O:6].[CH:23]([C:25]1[NH:29][C:28]([CH3:30])=[C:27]([C:31]([OH:33])=[O:32])[C:26]=1[CH3:34])=O>>[Cl:1][C:2]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:3]=1[CH2:4][S:5]([C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])/[C:11]/2=[CH:23]\[C:25]1[NH:29][C:28]([CH3:30])=[C:27]([C:31]([OH:33])=[O:32])[C:26]=1[CH3:34])(=[O:6])=[O:7]

Participants

3

Reactant 2

HCID 110737925-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic AcidHCID 18179715HCID 18179715, compound

Product 1

HCID 59077738HCID 59077738, compound

Procedure

5-[(2,5-Dichlorobenzyl)sulfonyl]-1,3-dihydro-indol-2-one was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid to give the titled compound as a yellow solid.

Sources & evidence

ORD record
ord-e0be9badf1604ded98ce81af68cf6156
Source dataset
uspto-grants-2003_07
Patent number
US06599902B2

Reaction notes

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