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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359786Generated: October 31, 2026

Ammonia → HCID 59077703, compound

https://huagongshe.com/reaction/1359786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 137178925HCID 137178925—
SolventDimethylacetamideHCID 31374—
ProductHCID 59077703HCID 59077703—

Reaction Steps

To a solution of 5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [1,2,3]triazolo[4,5-b]pyridin-3-yl ester (100 mg, 0.162 mmol) in DMA (2 mL) was added ammonia (2 eq.). The mixture was stirred at rt for 2 hours. The reaction was concentrated and triturated with methanol to give the titled compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-2eab6054780d4ed58c01a17518587d4e
Source noteuspto-grants-2003_07