Piperidine → HCID 59078877, compound

Participants

Reaction Steps

A mixture of 5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one (400 mg, 1.12 mmol), 2-(5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)-N-(1-methyl-piperidin-4-ylmethyl)-acetamide (295 mg, 1.2 q.) and piperidine (1.5 eq.) was stirred at rt for 96 hours. The reaction was concentrated and purified on a silica gel column to give the titled compound as a brown solid.

Provenance & Evidence