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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359889Generated: November 1, 2026

HCID 18179746, compound → HCID 59077714, compound

https://huagongshe.com/reaction/1359889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18179746HCID 18179746—
ReactantHCID 18179956HCID 18179956—
CatalystPiperidineHCID 8082—
SolventEthanolHCID 702—
ProductHCID 59077714HCID 5907771446%

Reaction Steps

5-[2-(2-Morpholin-4-yl-ethoxy)-phenylmethanesulfonyl]-1,3-dihydro-indol-2-one (39 mg, 0.094 mmol) was condensed with 4-[(cyclopropyl-methyl-amino)-methyl]-3,5-dimethyl-1H-pyrrole-2-carbaldehyde (21 mg, 0.1 mmol) and piperidine (1 drop) in ethanol (1.5 mL) at rt for 48 hours. The solvent was removed and the residue was purified on a silica gel column to give 26 mg (46%) of the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-065d2678e71d4bfda069d4e7d444821b
Source noteuspto-grants-2003_07