HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 23635280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Dichlorophosphoryloxynaphthalene | HCID 575631 | — |
| Reactant | L-Alanine, ethyl ester, hydrochloride (1:1) | HCID 2724356 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23635280 | HCID 23635280 | — |
Reaction Steps
Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.144 M) of 1-naphthyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1:1.1* mixture of diastereoisomers. 31P NMR (300 MHz, CDCl3) δ: 9.47 and 9.14*.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879815B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-7ba21c1a7b934bf3b41ff8466da5e769 |
| Source note | uspto-grants-2011_02 |