Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-chloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine | HCID 11738338 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Chloro-2-methyl-7-azaindole | HCID 21081675 | 72% |
Reaction Steps
A mixture of 4-chloro-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (4.73 g), potassium carbonate (6.4 g), methanol (45 ml), and water (15 ml) was stirred at 90° C. for 2 hours. After the mixture was cooled, the obtained needle crystals were filtered and washed with water to obtain 4-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine (1.85 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07879844B2 |
|---|
| Source dataset | uspto-grants-2011_02 |
|---|
| ORD ID | ord-00bc8e76fb284076b97a69894fbb7f2a |
|---|
| Source note | uspto-grants-2011_02 |
|---|
