Hydrochloric Acid → HCID 59755951, compound

Participants

Reaction Steps

Compound Y (88 mg, 0.2989 mmol, 1 eq) was dissolved in EtOH (2.0 ml) and 1N HCl was added (300 μl). Degassed solution 3 times with N2 and the Palladium catalyst (10 mg, 5% mmol) was added. Degassed with H2 (g) 3 times and hydrogenated for 90 minutes. The catalyst was filtered off and 1N HCl was added (300 μl). The solvent was removed in vacuo and taken up in water and lyophilized to obtain the desired compound as a yellow oil (59 mg, 82%). 1H NMR (400 MHz) D2O δ 3.88-3.68 (dm, 2H), 3.57-3.45 (m, 10H), 3.37-3.29 (m, 2H), 2.45 (m, 1H), 2.10 (m, 1H). 205.1 [M+H]+.

Provenance & Evidence