3-Dimethylaminobenzoyl chloride hydrochloride → n-[3-(6-Dibenzofuran-4-yl-pyrimidin-4-ylamino)-phenyl]-3-dimethylamino-benzamide

Participants

Reaction Steps

To a solution of N-(6-dibenzofuran-4-yl-pyrimidin-4-yl)-benzene-1,3-diamine trifluoroacetate (compound A2) (500 mg, 1.1 mmol) in pyridine (10 mL) is added at 10° C. 3-dimethylaminobenzoyl chloride HCl (288 mg, 1.21 mmol) portion wise. After 48 h at ambient temperature the mixture is evaporated and the crude product is purified by flash chromatography.

Provenance & Evidence