Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1360380생성일: 2026년 10월 27일
Dimethylformamide → 8-Bromo-3-methyl-7-(3-methylbut-2-enyl)-1-(2-oxo-2-phenylethyl)-3,7-dihydropurine-2,6-dione
https://huagongshe.com/reaction/1360380
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Phenacyl bromide | HCID 6259 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Methyl-7-(3-methyl-2-buten-1-yl)-8-bromo-xanthine | HCID 3435331 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 8-Bromo-3-methyl-7-(3-methylbut-2-enyl)-1-(2-oxo-2-phenylethyl)-3,7-dihydropurine-2,6-dione | HCID 24750161 | — |
반응 단계
30 g of 8-bromo-3-methyl-7-(3-methylbut-2-enyl)-3,7-dihydropurine-2,6-dione, 20.6 g of phenacyl bromide and 25.4 g of potassium carbonate are introduced into 400 ml of DMF and heated at an internal temperature of 80° C. for 3 hours. The solution is cooled to about 50° C., and 400 ml of water are slowly added. The mixture is then stirred overnight, and precipitated solid is filtered off with suction. After washing the water, the pale brown solid is recrystallized from 300 ml of isopropanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07879864B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_02 |
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| ORD ID | ord-5e2c655aa8034e8da5fc300eda65f90c |
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| 출처 메모 | uspto-grants-2011_02 |
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