HCID 57855484, compound → HCID 16660449, compound

Participants

Reaction Steps

A solution of N-((2E)-3-(2-furyl)-1-{[(7-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl]methyl}prop-2-en-1-yl)-N-hydroxyformamide (30 mg, 0.073 mmol) in MeOH (3 ml) was hydrogenated over 10% Pd/C under 5 bars of hydrogen for 2 hours. The reaction mixture was filtered and the solvent was evaporated under reduced pressure to give the title compound (33) as a colorless oil (10 mg, 33%). HPLC, Rt: 3.2 min (purity: 84.3%). LC/MS, M+(ESI): 413.3, M−(ESI): 411.2.

Provenance & Evidence