HCID 86630234, compound → HCID 66962728, compound

HRID 1360661Notes

Reaction equation

HRID 1360661 reaction equation
C(OC(=O)[NH:10][CH:11]1[CH:18]2[CH:14]([O:15][C:16]([CH3:20])([CH3:19])[O:17]2)[CH:13]([O:21][Si:22]([C:25]([CH3:28])([CH3:27])[CH3:26])([CH3:24])[CH3:23])[CH2:12]1)C1C=CC=CC=1>CCO.[C].[Pd]>[Si:22]([O:21][CH:13]1[CH:14]2[O:15][C:16]([CH3:20])([CH3:19])[O:17][CH:18]2[CH:11]([NH2:10])[CH2:12]1)([C:25]([CH3:28])([CH3:26])[CH3:27])([CH3:23])[CH3:24]

Participants

4

Reactant 1

HCID 86630234HCID 86630234, compound

Product 1

HCID 66962728HCID 66962728, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

Palladium-carbon (10%) was added to a solution of benzyl((3aRS,4SR,6RS,6aRS)-6-{[tert-butyl(dimethyl)silyl]oxy}-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)carbamate in EtOH, for stirring overnight under hydrogen atmosphere, to obtain (3aRS,4SR,6RS,6aRS)-6-{[tert-butyl(dimethyl)silyl]oxy}-2,2-dimethyltetrahydro-3 aH-cyclopenta[d][1,3]dioxol-4-amine.

Sources & evidence

ORD record
ord-2e2191f5bc4e4628ab14fcb0fa065f10
Source dataset
uspto-grants-2011_02
Patent number
US07879878B2

Reaction notes

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