Oxalyl chloride → HCID 16064894, compound

Participants

Reaction Steps

To a solution of 3-[6-(2,4-difluorophenyl)-2-oxo-2H-quinolizin-1-yl]-4-fluorobenzoic acid (Example 31, 15 mg, 0.04 mmol) in MeOH (2 mL) was added oxalyl chloride dropwise at 0° C. The reaction mixture was allowed to warm to ambient temperature for 12 h. The mixture was concentrated and the crude material was purified via silica gel chromatography (100% EtOAc).

Provenance & Evidence