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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13608Generated: October 28, 2026

(S)-2-Amino-3-(4'-methyl-biphenyl-4-yl)-propionic acid methyl ester hydrochloride → HCID 66923066, compound

https://huagongshe.com/reaction/13608

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-Amino-3-(4'-methyl-biphenyl-4-yl)-propionic acid methyl ester hydrochlorideHCID 66719510—
ReactantHCID 66923012HCID 66923012—
ProductHCID 66923066HCID 66923066—

Reaction Steps

(S)-2-({(S)-3-[4-(3,4-Dichloro-benzyloxy)-phenyl]-2-oxo-2,3,5,6,7,8-hexahydro-1H-4-oxa-1,6-diaza-anthracene-7-carbonyl}-amino)-3-(4′-methyl-biphenyl-4-yl)-propionic acid methyl ester hydrochloride (74 mg, LC/MS: m/z 751) was prepared from (S)-3-[4-(3,4-Dichloro-benzyloxy)-phenyl]-2-oxo-1,2,3,5,7,8-hexahydro-4-oxa-1,6-diaza-anthracene-6,7-dicarboxylic acid 6-tert-butyl ester (150 mg) and (S)-2-Amino-3-(4′-methyl-biphenyl-4-yl)-propionic acid methyl ester hydrochloride according to general procedures A and C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727983B2
Source datasetuspto-grants-2010_06
ORD IDord-1d14edab3e62415285fb545003e14854
Source noteuspto-grants-2010_06