cis-(4-Cyclobutyl-piperazin-1-yl)-(4-hydroxy-cyclohexyl)-methanone → cis-[4-(5-Chloro-pyridin-2-yloxy)-cyclohexyl]-(4-cyclobutyl-piperazin-1-yl)-methanone
Reaction equation
[CH:1]1([N:5]2[CH2:6][CH2:7][N:8]([C:11](=[O:12])[CH:13]3[CH2:14][CH2:15][CH:16]([OH:19])[CH2:17][CH2:18]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1.[Cl:20][c:21]1[cH:22][cH:23][c:24]([OH:27])[n:25][cH:26]1>>[CH:1]1([N:5]2[CH2:6][CH2:7][N:8]([C:11](=[O:12])[CH:13]3[CH2:14][CH2:15][CH:16]([O:19][c:24]4[cH:23][cH:22][c:21]([Cl:20])[cH:26][n:25]4)[CH2:17][CH2:18]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4]1Participants
3
Sources & evidence
- ORD record
- ord-d868302303834744b4635eac085f1240
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…