Thiazolidinedione → 5-[(3-Phenoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione

Participants

Reaction Conditions

Reaction Steps

A solution of thiazolidine-2,4-dione (90%, 78 mg, 0.6 mmol) and ammonium acetate (92 mg, 1.2 mmol) in acetic acid (1 mL) was added to 3-phenoxybenzaldehyde (52 μL, 0.6 mmol) and the resulting mixture was shaken at 115° C. for 16 hours. After cooling, the mixture was concentrated in vacuo to afford the title compound.

Provenance & Evidence