Thiazolidinedione → HCID 76542788, compound

HRID 1360993Notes

Reaction equation

HRID 1360993 reaction equation
[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10]Br)=[CH:6][CH:5]=1.[CH3:13][C:14]1[NH:15][C:16]2[C:21]([C:22]=1[CH:23]=O)=[CH:20][CH:19]=[CH:18][CH:17]=2.[S:25]1[CH2:29][C:28](=[O:30])[NH:27][C:26]1=[O:31]>>[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10][N:15]2[C:16]3[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:22]([CH:23]=[C:29]3[S:25][C:26](=[O:31])[NH:27][C:28]3=[O:30])=[C:14]2[CH3:13])=[CH:6][CH:5]=1

Participants

4

Reactant 3

HCID 5437ThiazolidinedioneHCID 731663-Formyl-2-methylindoleHCID 256687Methyl 4-(bromomethyl)benzoate

Product 1

HCID 76542788HCID 76542788, compound

Procedure

This compound was prepared in analogy with the compound described in example 200 from 4-(bromomethyl)benzoic acid methyl ester and 2-methylindole-3-carbaldehyde, followed by reaction with thiazolidine-2,4-dione.

Workup

  1. customThis compound was prepared in analogy with the compound

Sources & evidence

ORD record
ord-9b6a6dd6a44b421b965d4a7d1bdbe6ec
Source dataset
uspto-grants-2011_02
Patent number
US07879893B2

Reaction notes

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