HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxy-2-naphthoic acid → 3-Hydroxy-4-iodonaphthalene-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxy-2-naphthoic acid | HCID 7104 | — |
| Reactant | Iodine chloride | HCID 24640 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Hydroxy-4-iodonaphthalene-2-carboxylic acid | HCID 242251 | 85% |
Reaction Steps
3-Hydroxynaphthalene-2-carboxylic acid (0.5 g, 2.7 mmol) was suspended in acetic acid (5 mL) and with stirring iodine monochloride (135 μL, 2.7 mml) was added. The suspension was stirred at room temperature for 1 hour, filtered and washed with water. Drying afforded 0.72 g (85%) of 4-iodo-3-hydroxynaphthalene-2-carboxylic acid as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879893B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-299bc2d3ad86405fbcba1407a57321f8 |
| Source note | uspto-grants-2011_02 |