Ethanol → HCID 87216990, compound

HRID 1361101Notes

Reaction equation

HRID 1361101 reaction equation
N[CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][NH2:10].[CH3:11][Si:12]([CH3:27])([CH2:21][CH2:22][Si:23]([CH3:26])([CH3:25])[CH3:24])[CH2:13][CH2:14][CH2:15][O:16][CH2:17][CH:18]1[CH2:20][O:19]1.C([OH:30])C>>[CH3:11][Si:12]([CH3:27])([CH2:21][CH2:22][Si:23]([CH3:26])([CH3:25])[CH3:24])[CH2:13][CH2:14][CH2:15][O:16][CH2:17][CH:18]([OH:19])[CH2:20][NH:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2][OH:30]

Participants

4

Reactant 3

HCID 702Ethanol3×HCID 70248Bis-AminoethylglycolHCID 597587042-{3-[Dimethyl-(2-trimethylsilanyl-ethyl)-silanyl]-propoxymethyl}-oxirane

Product 1

HCID 87216990HCID 87216990, compound

Conditions

Temperature
70 °C

Procedure

2-[2-(2-Amino-ethoxy)-ethoxy]-ethylamine (5.40 g; 36.4 mMol) and 40 mL of ethanol were charged to a 100 ml RB flask equipped with a magnetic stirrer. The mixture was stirred and heated to 70° C. 2-{3-[Dimethyl-(2-trimethylsilanyl-ethyl)-silanyl]-propoxymethyl}-oxirane 8 (2 g; 7.28 mMol) mixed with 10 g ethanol was placed in an addition funnel and added dropwise to the flask. The mixture was stirred and maintained at 70° C. for an additional 4 hours. Ethanol was stripped off on the rotovap. The mixture was distilled under vacuum to remove impurities and excess raw material.

Workup

  1. customequipped with a magnetic stirrer
  2. customwas placed in an addition funnel
  3. additionadded dropwise to the flask
  4. stirringThe mixture was stirred
  5. temperaturemaintained at 70° C. for an additional 4 hours
  6. distillationThe mixture was distilled under vacuum
  7. customto remove impurities and excess raw material

Sources & evidence

ORD record
ord-1a0fea1aa6a341cf80c19b2111ee4487
Source dataset
uspto-grants-2011_02
Patent number
US07879916B2

Reaction notes

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