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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1361287Generated: October 30, 2026

HCID 66971163, compound → HCID 66971424, compound

https://huagongshe.com/reaction/1361287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66971163HCID 66971163—
CatalystPalladiumHCID 23938—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66971424HCID 6697142498.5%

Reaction Steps

To a solution of (2S,4S)-1-Boc-2-allyl-4-aminopyrrolidine (450 mg, 1.78 mmol) prepared in Preparation Example A1-4 in dioxane (5 mL) was added Pd/C (40 mg). The reaction mixture was stirred under hydrogen condition for 24 h, filtered through Celite, and the filtrate was concentrated in vacuo to give the title compound as an oil (390 mg, 98.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07879852B2
Source datasetuspto-grants-2011_02
ORD IDord-c71758026c8543378a7ba4a50ac8ea12
Source noteuspto-grants-2011_02