HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66971163, compound → HCID 66971424, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66971163 | HCID 66971163 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66971424 | HCID 66971424 | 98.5% |
Reaction Steps
To a solution of (2S,4S)-1-Boc-2-allyl-4-aminopyrrolidine (450 mg, 1.78 mmol) prepared in Preparation Example A1-4 in dioxane (5 mL) was added Pd/C (40 mg). The reaction mixture was stirred under hydrogen condition for 24 h, filtered through Celite, and the filtrate was concentrated in vacuo to give the title compound as an oil (390 mg, 98.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879852B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-c71758026c8543378a7ba4a50ac8ea12 |
| Source note | uspto-grants-2011_02 |