N-Methylethylamine → HCID 66971195, compound

HRID 1361304Notes

Reaction equation

[C:1]([N:8]1[CH2:15][C@@H:14]([N:16]([CH:24]2[CH2:29][CH2:28][C:27]([CH3:31])([CH3:30])[CH2:26][CH2:25]2)[C:17](=[O:23])[C:18]([CH3:22])([CH3:21])[CH2:19][OH:20])[CH2:13][C@H:9]1[C:10]([OH:12])=O)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[CH3:32][NH:33][CH2:34][CH3:35]>>[C:1]([N:8]1[CH2:15][C@@H:14]([N:16]([CH:24]2[CH2:29][CH2:28][C:27]([CH3:30])([CH3:31])[CH2:26][CH2:25]2)[C:17](=[O:23])[C:18]([CH3:21])([CH3:22])[CH2:19][OH:20])[CH2:13][C@H:9]1[C:10]([N:33]([CH2:34][CH3:35])[CH3:32])=[O:12])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:2]

Participants

Reactant 2

HCID 12219N-Methylethylamine

HCID 66971194HCID 66971194, compound

Product 1

HCID 66971195HCID 66971195, compound

Procedure

The title compound was prepared according to the procedure described in Step D of Example A1 using (4S)-1-BOC-4-[(4,4-dimethylcyclohexyl)(3-hydroxy-2,2-dimethylpropanoyl)amino]-L-pr oline (0.85 g, 1.94 mmol) prepared in Step B and commercially available N-methylethylamine (0.86 g, 93%).

Sources & evidence

ORD record: ord-2c0333f39627432a9ade879c7612aca8
Source dataset: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07879852B2

Reaction notes

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