HRID1361334

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)C(=O)[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C

HCID86636654

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)[C@@H]1C[C@H](N)CN1C(=O)OC(C)(C)C

HCID66971238

未命名化合物

收率 98.5%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

To a solution of (2S,4S)-1-Boc-4-azido[(dimethylamino)carbonyl]pyrrolidine (9 g, 32 mmol) prepared in Step B in dioxane (30 mL) was added dropwise Pd/C (900 mg). The reaction mixture was stirred under hydrogen condition for 24 h, filtered through Celite, and concentrated in vacuo to give the title compound as an oil (8.1 g, 98.5%).

WORKUP

后处理

filtrationfiltered through Celite
concentrationconcentrated in vacuo