Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776291, compound

HRID 1361538Notes

Reaction equation

HRID 1361538 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:21]=[CH:22][CH:23]=1)[O:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([O:15][C@@H:16]([CH3:20])[CH2:17][O:18][CH3:19])[CH:14]=1)[C:9]([OH:11])=O.[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH2:35])=[N:32][CH:31]=1)[CH3:25]>>[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH:35][C:9](=[O:11])[C:8]2[CH:12]=[C:13]([O:15][C@@H:16]([CH3:20])[CH2:17][O:18][CH3:19])[CH:14]=[C:6]([O:5][C:4]3[CH:21]=[CH:22][CH:23]=[C:2]([F:1])[CH:3]=3)[CH:7]=2)=[N:32][CH:31]=1)[CH3:25]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 66970052HCID 66970052, compound

Product 1

HCID 57776291HCID 57776291, compound

Procedure

The title compound was prepared from 3-(3-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-f39bca3143244fd3935f9f575ca7e53c
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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