Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776330, compound

HRID 1361542Notes

Reaction equation

HRID 1361542 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([O:18][C@@H:19]([CH3:23])[CH2:20][O:21][CH3:22])[CH:17]=1)[C:12]([OH:14])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH2:35])=[N:32][CH:31]=1)[CH3:25]>>[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH:35][C:12](=[O:14])[C:11]2[CH:15]=[C:16]([O:18][C@@H:19]([CH3:23])[CH2:20][O:21][CH3:22])[CH:17]=[C:9]([O:8][CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:10]=2)=[N:32][CH:31]=1)[CH3:25]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 59127150Benzoic acid, 3-[(1S)-2-methoxy-1-methylethoxy]-5-(phenylmethoxy)-

Product 1

HCID 57776330HCID 57776330, compound

Procedure

The title compound was prepared from 3-benzyloxy-5-((S)-2-methoxy-1-methylethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-0f445b52ebf54c1384bcaa8672fe6bc5
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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